Evertor Everolimus

Product Description

Evertor (Everolimus)  

Brand name: Evertor

Active Ingeridents(Generic Name) :Everolimus   

Company Name: Biocon

Package: 10 tabs in a strip

Strength : 5mg

Indication:

Evertor (Everolimus)   is  used to treat a certain type of advanced breast cancer that has already been treated with at least one other medication. Evertor (Everolimus)    is also used to treat a certain type of cancer of the pancreas that has spread or progressed and that cannot be treated with surgery

Mechanism of action:

Evertor (Everolimus)    is a mTOR inhibitor that binds with high affinity to the FK506 binding protein-12 (FKBP-12), thereby forming a drug complex that inhibits the activation of mTOR. This inhibition reduces the activity of effectors downstream, which leads to a blockage in the progression of cells from G1 into S phase, and subsequently inducing cell growth arrest and apoptosis. Evertor (Everolimus)   also inhibits the expression of hypoxia-inducible factor, leading to a decrease in the expression of vascular endothelial growth factor. The result of Evertor (Everolimus)   inhibition of mTOR is a reduction in cell proliferation, angiogenesis, and glucose uptake.

Dosage and Administration:

• Evertor (Everolimus)      is given as a tablet by mouth.

• Take at the same time each day, may be taken with or without food.

• Swallow whole with a glass of water, do not chew or crush tablets.

• Avoid contact with or exposure to crushed or broken tablets.

• The amount of Evertor (Everolimus)    that you will receive will be prescribed by your doctor based on established dosing guidelines.

Side effects:

Stop using Evertor (Everolimus)   and call your doctor at once if you have: Common Evertor (Everolimus)    side effects may include:

·         infections, cough, nosebleeds;  mouth sores, taste problems, dry mouth;  nausea, vomiting, diarrhea, constipation;  weight loss, feeling weak or tired;,  pain or swelling anywhere in your body; dry skin, rash, acne;  missed menstrual periods; unusual changes in mood or behavior; sleep problems (insomnia);  dizziness, headache; high blood sugar - increased thirst or urination, hunger, fruity breath odor, blurred vision.

Precaution:

• Before starting Evertor (Everolimus)    treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).

• Do not receive any kind of immunization or vaccination without your doctor’s approval while taking Evertor (Everolimus)  .

Store: Evertor (Everolimus)   room temperature away from moisture and heat